Product Introduction:
Zentim Injection contains Imipenem (1 gm) and Cilastatin (125 mg). Imipenem is a broad-spectrum carbapenem antibiotic effective against a wide range of bacteria, while Cilastatin helps prevent the breakdown of Imipenem in the kidneys, enhancing its efficacy.
Uses:
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Lower respiratory tract infections
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Intra-abdominal infections
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Urinary tract infections
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Skin and soft tissue infections
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Gynecological infections
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Septicemia
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Bone and joint infections
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Nosocomial infections
Benefits:
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Broadest antibacterial spectrum among beta-lactams
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Effective against multidrug-resistant bacteria
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Useful in severe hospital-acquired infections
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Cilastatin increases the effectiveness and duration of Imipenem
Composition (per vial):
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Imipenem 1 gm
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Cilastatin 125 mg
Side Effects:
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Nausea and vomiting
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Diarrhea
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Injection site reactions
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Rash
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Seizures (rare, especially in renal impairment or high doses)
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Headache
Safety Advice:
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For intravenous use only, under medical supervision
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Adjust dose in patients with kidney dysfunction
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Monitor for signs of allergy or neurological effects
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Complete the course even if symptoms improve
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Avoid in patients with known beta-lactam allergy
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Store below 25°C; protect from moisture and light
