Product Introduction:
Metride-PL Tablet combines three oral antidiabetic agents that work in synergy to control blood glucose in adults with type 2 diabetes. It enhances insulin secretion, reduces glucose production in the liver, and improves insulin sensitivity in muscle and fat tissues. It is part of comprehensive diabetes management including diet and exercise.
Uses:
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Type 2 diabetes mellitus (non-insulin dependent)
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Especially for patients not responding to dual therapy (e.g., Metformin + Glimepiride or Metformin + Pioglitazone)
Benefits:
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Triple mechanism for better blood sugar control
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Helps reduce fasting and post-meal glucose
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Delays or reduces the risk of diabetic complications
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Convenient once-daily dosing in most cases
Composition (per tablet):
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Glimepiride – 2 mg
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Metformin Hydrochloride (SR) – 500 mg
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Pioglitazone – 7.5 mg
Side Effects:
Common:
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Nausea, vomiting
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Stomach upset or diarrhea
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Weight gain (due to Pioglitazone)
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Low blood sugar (hypoglycemia, especially with missed meals)
Occasional:
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Edema (fluid retention)
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Headache
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Mild anemia
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Increased risk of bone fracture (long-term use)
Rare:
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Liver dysfunction
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Heart failure (in predisposed individuals)
Safety Advice:
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Take with food, preferably with breakfast
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Monitor blood sugar levels regularly
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Not recommended in type 1 diabetes or diabetic ketoacidosis
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Use cautiously in patients with heart, liver, or kidney disease
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Avoid alcohol as it increases the risk of lactic acidosis
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Not suitable in pregnancy or breastfeeding unless advised
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Store in a cool, dry place
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Keep out of reach of children
