Product Introduction
Endoprost 250 mcg Injection is a prostaglandin F2α analogue, containing Carboprost Tromethamine. It is primarily used in gynecology and obstetrics to terminate pregnancy (up to 20 weeks) and to control excessive bleeding after childbirth (PPH) when other treatments have failed. It works by stimulating strong uterine contractions, helping the uterus return to normal tone and expel retained products.
Uses
- Medical termination of pregnancy (up to 20 weeks gestation)
- Management of postpartum hemorrhage (PPH)
- Induction of labor in special medical cases (under specialist supervision)
- Expulsion of retained placental fragments
Benefits
- Effectively induces uterine contractions for medical abortion
- Helps reduce and stop excessive bleeding after childbirth
- Can be used when oxytocin or ergometrine are ineffective
- A valuable emergency drug in obstetric care settings
Composition
- Carboprost Tromethamine – 250 mcg/ml
Side Effects
Common side effects:
- Nausea and vomiting
- Diarrhea
- Abdominal cramps
- Flushing or hot flashes
- Fever or chills
Serious (but less common) side effects:
- Increased blood pressure
- Breathing difficulty (bronchospasm, especially in asthmatic patients)
- Uterine rupture (very rare, with improper use)
- Allergic reactions (rash, swelling, anaphylaxis)
- Seek immediate medical help if any serious adverse reaction occurs.
Safety Advice
- Administered only by trained healthcare professionals in hospital settings
- Not recommended in patients with asthma, hypertension, heart, kidney, or liver disease without medical supervision
- Monitor vital signs and uterine activity during administration
- Should not be used beyond recommended gestational age
- Avoid use during pregnancy unless intended for abortion or emergency obstetric intervention
- Store in a refrigerator (2–8°C); do not freeze
